A

Aiello, Stefania, Wells, Geoffrey, Stone, Erica L., Kadri, Hachemi, Bazzi, Rana, Bell, David R., Stevens, Malcolm F. G., Matthews, Charles S., Bradshaw, Tracey D. and Westwell, Andrew D. (2008) Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648). Journal of Medicinal Chemistry, 51(16), pp. 5135-5139. ISSN (print) 0022-2623

Almasri, Moayad (2008) Liquid crystalline conducting polymers. (PhD thesis), Kingston University, .

B

Balding, Philip, R., Porro, Cristina, S., McLean, Kirsty, J., Sutcliffe, Michael, J., Maréchal, Jean-Didier, Munro, Andrew, W. and de Visser, Sam, P. (2008) How do azoles inhibit cytochrome P450 enzymes? A density functional study. Journal of Physical Chemistry A, 112(50), pp. 12911-12918. ISSN (print) 1089-5639

Busquets, Rosa, Mitjans, David, Puignou, Lluís and Galceran, Maria Teresa (2008) Quantification of heterocyclic amines from thermally processed meats selected from a small-scale population-based study. Molecular Nutrition and Food Research, 52(12), pp. 1408-1420. ISSN (print) 1613-4125

C

Calabrese, Gianpiero, Gomes, Ana C. N. M., Barbu, Eugen, Nevell, Thomas G. and Tsibouklis, John (2008) Carborane-based derivatives of delocalised lipophilic cations for boron neutron capture therapy: synthesis and preliminary in vitro evaluation. Journal of Materials Chemistry, 18(40), pp. 4864-4871. ISSN (print) 0959-9428

Cartledge, Timothy (2008) Synthesis, biochemical evaluation and physiochemical property determination of a range of potential estrone sulfatase inhibitors in the treatment of hormone-dependent breast cancer. (PhD thesis), Kingston University, .

Casey, Duncan R., Sebai, Sarra C., Shearman, Gemma C., Ces, Oscar, Law, Robert V., Templer, Richard H. and Gee, Antony D. (2008) Formulation affects the rate of membrane degradation catalyzed by cationic amphiphilic drugs. Industrial and Engineering Chemistry Research, 47(3), pp. 650-655. ISSN (print) 0888-5885

Chan, J., Craig, J.P., Elmaghraby, G.M.M. and Alany, R.G. (2008) Effect of water-in-oil microemulsions and lamellar liquid crystalline systems on the precorneal tear film of albino New Zealand rabbits. Clinical Ophthamology, 2(1), pp. 129-137. ISSN (print) 1177-5467

Chohan, Magali, Forster-Wilkins, Gary and Opara, Elizabeth I (2008) Determination of the antioxidant capacity of culinary herbs subjected to various cooking and storage processes using the ABTS[sup]*+ radical cation assay. Plant Foods for Human Nutrition, 63(2), pp. 47-52. ISSN (print) 0921-9668

Coldwell, Beverley Claire (2008) Evolution of the Peruvian subduction margin at 9[degrees]S: evidence from geochemistry, experimental pterology and melt inclusion studies on adakite-like ignimbrites. (PhD thesis), Kingston University, .

D

Davis, M. and Koenders, M.A. (2008) Combined gravity and mean flow effects on agitated slurries in a dead-end filtration set-up. Powder Technology, 182(2), pp. 307-312. ISSN (print) 0032-5910

Davis, M., Koenders, M. and Vahid, S. (2008) Granular temperature model for oscillated slurries: a cell model. Institution of Mechanical Engineers. Proceedings. Part C: Journal of Mechanical Engineering Science, 222(10), pp. 1995-2006. ISSN (print) 0954-4062

Disch, Benoit A. (2008) Calibration of LA-ICP-MS for trace element analysis of phosphate materials. (MSc(R) thesis), Kingston University, .

Dyrka, Witold, Augousti, Andy T. and Kotulska, Malgorzata (2008) Ion flux through membrane channels: an enhanced algorithm for the Poisson-Nernst-Planck model. Journal of Computational Chemistry, 29(12), pp. 1876-1888. ISSN (print) 0192-8651

F

Franke, Susanne, Malcolmson, Carole, Bunt, Craig, Rupenthal, Ilva and Alany, Raid (2008) Imaging techniques and their role in dosage form design and drug delivery research. Current Pharmaceutical Analysis, 4(3), pp. 118-125. ISSN (print) 1573-4129

G

Georgiades, Savvas and Clardy, Jon (2008) Synthetic libraries of tyrosine-derived bacterial metabolites. Bioorganic & Medicinal Chemistry Letters, 18(10), pp. 3117-3121. ISSN (print) 0960-894X

Ghatora, Baljit, Foot, Peter, Barton, Stephen and Kishi, Mariko (2008) Investigation into the causes of post-operative calcification in intraocular lenses. In: Institute of Materials, Minerals and Mining Annual Conference 2008; 13-15 May 2008, Grantham, U.K..

H

Hague, Theresa, Petroczi, Andrea, Andrews, Paul L.R., Barker, James and Naughton, Declan P. (2008) Determination of metal ion content of beverages and estimation of target hazard quotients : a comparative study. Chemistry Central Journal, 2(13), ISSN (online) 1752-153X

Hay, Sam, Pudney, Christopher, R., Sutcliffe, Michael, J. and Scrutton, Nigel, S. (2008) Are environmentally coupled enzymatic hydrogen tunneling reactions influenced by changes in solution viscosity? Angewandte Chemie - International Edition, 47(3), pp. 537-540. ISSN (print) 1433-7851

Hay, Sam, Pudney, Christopher, Hothi, Parvinder, Johannissen, Linus, O., Masgrau, Laura, Pang, Jiayun, Leys, David, Sutcliffe, Michael, J. and Scrutton, Nigel, S. (2008) Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation. Biochemical Society Transactions, 36(1), pp. 16-21. ISSN (print) 0300-5127

Hay, Sam, Pang, Jiayun, Monaghan, Phillip, J., Wang, Xi, Evans, Rhiannon, M., Sutcliffe, Michael, J., Allemann, Rudolf, K. and Scrutton, Nigel, S. (2008) Secondary kinetic isotope effects as probes of environmentally-coupled enzymatic hydrogen tunneling reactions. ChemPhysChem, 9(11), pp. 1536-1539. ISSN (print) 1439-4235

Hay, Sam, Pudney, Christopher, R., Sutcliffe, Michael, J. and Nigel, Nigel, S. (2008) Solvent as a probe of active site motion and chemistry during the hydrogen tunnelling reaction in morphinone reductase. ChemPhysChem, 9(13), pp. 1875-1881. ISSN (print) 1439-4235

Hothi, Parvinder, Hay, Sam, Roujeinikova, Anna, Sutcliffe, Michael, J., Lee, Michael, Leys, David, Cullis, Paul, M. and Scrutton, Nigel, S. (2008) Driving force analysis of proton tunnelling across a reactivity series for an enzyme-substrate complex. Chembiochem : a European journal of chemical biology, 9(17), pp. 2839-2845. ISSN (print) 1439-4227

I

Ioakimidis, Leukothea, Thoukydidis, Loizos, Mirza, Amin, Naeem, Saira and Reynisson, Johannes (2008) Benchmarking the reliability of QikProp. Correlation between experimental and predicted values. QSAR & Combinatorial Science, 27(4), pp. 445-456. ISSN (print) 1611-020X

J

Johannissen, Linus, O., Scrutton, Nigel, S. and Sutcliffe, Michael, J. (2008) The enzyme aromatic amine dehydrogenase induces a substrate conformation crucial for promoting vibration that significantly reduces the effective potential energy barrier to proton transfer. Journal of the Royal Society Interface, 5(SUPPL. 3), S225-S232. ISSN (print) 1742-5689

K

Kadri, H., Dale, T.C., Ewan, K.B.R. and Westwell, A.D. (2008) The design, synthesis and antitumour evaluation of novel small molecule inhibitors of the Dishevelled PDZ domain. European Journal of Cancer Supplements, 6(12), p. 137. ISSN (print) 1359-6349

Kadri, Hachemi, Matthews, Charles S., Bradshaw, Tracey D., Stevens, Malcolm F. G. and Westwell, Andrew D. (2008) Synthesis and antitumour evaluation of novel 2- phenylbenzimidazoles. Journal of Enzyme Inhibition and Medicinal Chemistry, 23(5), pp. 641-647. ISSN (print) 1475-6366

Kapelyukh, Yury, Paine, Mark, J.I., Maréchal, Jean-Didier, Sutcliffe, Michael, J., Wolf, C. Roland and Roberts, Gordon, C.K. (2008) Multiple substrate binding by cytochrome P450 3A4: Estimation of the number of bound substrate molecules. Drug Metabolism and Disposition, 36(10), pp. 2136-2144. ISSN (print) 0090-9556

Karlyshev, Andrey, Wren, Brendan W and Moran, Anthony P (2008) Campylobacter jejuni Capsular Polysaccharide. In: Nachamkin, Irving , Szymanski, Christine M. and Blaser, Martin J., (eds.) Campylobacter. 3rd edition. Washington, DC, USA : American Society for Microbiology Press,. pp. 505-522. ISBN 9781555814373

Khan, Mohammad Rizwan, Busquets, Rosa, Santos, Francisco Javier and Puignou, Lluís (2008) New method for the analysis of heterocyclic amines in meat extracts using pressurised liquid extraction and liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, 1194(2), pp. 155-160. ISSN (print) 0021-9673

Koenders, M.A. and Gaspar, N. (2008) The auxetic properties of a network of bending beams. physica status solidi b, 245(3), pp. 539-544. ISSN (print) 0370-1972

Kuhnert, Nikolai and Le Gresley, Adam (2008) Synthesis of upper rim calix[4]arene carcerands. Tetrahedron Letters, 49(7), pp. 1274-1276. ISSN (print) 0040-4039

L

Labate, Massimiliano, Foot, Peter J.S., O'Malley, Hugh, Miozzo, Luciano, Papagni, Antonio, Silvestri, Leonardo, Spearman, P. and Tavazzi, Silvia (2008) Inorganic/organic semiconductor heterostructures: optical properties of quaterthiophene intercalated in cadmium phosphorus trisulfide. The Journal of Physical Chemistry C, 112(51), pp. 20149-20153. ISSN (print) 1932-7447

Lai, Cheng-Yuan, Foot, Peter J.S. and Brown, John W. (2008) The synthesis of novel electrochromic materials to increase the colour-changing service life of poly(3-hexylthiophene), and investigation of their optical and electrical properties. In: 59th Annual Meeting of the International Society of Electrochemistry; 7 - 12 Sept 2008, Seville, Spain. (Unpublished)

Lota, Rupinder K., Olusanjo, Moniola S., Dhanani, Sachin, Owen, Caroline P. and Ahmed, Sabbir (2008) Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of 4-hydroxyphenyl ketones as potent and specific inhibitors of the type 3 of 17[beta]-hydroxysteroid dehydrogenase (17[beta]-HSD3). The Journal of Steroid Biochemistry and Molecular Biology, 111(1-2), pp. 128-137. ISSN (print) 0960-0760

M

McKinnon, William, Pentecost, C, Lord, Gwyn A, Forni, Lui G, Peron, Jean-Marie and Hilton, Philip J (2008) Elevation of anions in exercise-induced acidosis: a study by ion-exchange chromatography/mass spectrometry. Biomedical Chromatography, 22(3), pp. 301-305. ISSN (print) 0269-3879

McLaughlin, L.A., Niazi, U., Bibby, J., David, J.P., Vontas, J., Hemingway, J., Ranson, H., Sutcliffe, M.J. and Paine, M.J.I. (2008) Characterization of inhibitors and substrates of Anopheles gambiae CYP6Z2. Insect Molecular Biology, 17(2), pp. 125-135. ISSN (print) 0962-1075

Meng, Dan, Falconer, James, Krauel-Goellner, Karen, Chen, John J. J. J., Farid, Mohammed and Alany, Raid G. (2008) Self-built supercritical CO2 anti-solvent unit design, construction and operation using carbamazepine. AAPS PharmSciTech, 9(3), pp. 944-952. ISSN (online) 1530-9932

Merzouk, Mahboub (2008) Synthesis of chiral iminoalkyl functionalised N-Heterocyclic carbenes and their use in asymmetric catalysis. (PhD thesis), Kingston University, .

O

Olusanjo, Moniola Sarah (2008) Synthesis and biochemical evaluation of potential steroidal and non-steroidal inhibitors of 17[beta]-hydroxysteroid dehydrogenase (17[beta]-HSD) in the treatment of hormone-dependent cancers. (PhD thesis), Kingston University, .

P

Pang, Jiayun, Hay, Sam, Scrutton, Nigel, S. and Sutcliffe, Michael, J. (2008) Deep tunneling dominates the biologically important hydride transfer reaction from NADH to FMN in morphinone reductase. Journal of the American Chemical Society, 130(22), pp. 7092-7097. ISSN (print) 0002-7863

Pillai, Seema Sudhakaran, Foot, Peter J.S. and Kresinski, Roman A. (2008) Conducting polymer-lanthanide composites for luminescent devices. In: 59th Annual Meeting of the International Society of Electrochemistry; 7 - 12 Sept 2008, Seville, Spain. (Unpublished)

R

Ranuncolo, Stella Maria, Wang, Ling, Polo, Jose M., Dell'Oso, Tania, Dierov, Jamil, Gaymes, Terry, Rassool, Feyruz, Carroll, Martin and Melnick, Ari (2008) BCL6 mediated attenuation of DNA damage sensing triggers growth arrest and senescence through a 53-dependent pathway in a cell-context dependent manner. The Journal of Biological Chemistry, 283(33), pp. 22565-22572. ISSN (print) 0021-9258

Roberts, Jonathan, A., Digby, Helen, R., Kara, Madina, El Ajouz, Sam, Sutcliffe, Michael, J. and Evans, Richard, J. (2008) Cysteine substitution mutagenesis and the effects of methanethiosulfonate reagents at P2X2 and P2X4 receptors support a core common mode of ATP action at P2X receptors. Journal of Biological Chemistry, 283(29), pp. 20126-20136. ISSN (print) 0021-9258

S

Sattelle, Benedict, M. and Sutcliffe, Michael, J. (2008) Calculating chemically accurate redox potentials for engineered flavoproteins from classical molecular dynamics free energy simulations. Journal of Physical Chemistry A, 112(50), pp. 13053-13057. ISSN (print) 1089-5639

Shahid, Imran, Patel, Chirag H., Dhanani, Sachin, Owen, Caroline P. and Ahmed, Sabbir (2008) Synthesis, biochemical evaluation of a range of potent 4-substituted phenyl alkyl imidazole-based inhibitors of the enzyme complex 17[alpha]-Hydroxylase/17,20-Lyase (P450[sub]17[alpha]). The Journal of Steroid Biochemistry and Molecular Biology, 110(1-2), pp. 18-29. ISSN (print) 0960-0760

Shoshtari, Sara, Wen, Jingyuan and Alany, Raid G. (2008) Octanol water partition coefficient determination for model steroids using an HPLC method. Letters in Drug Design & Discovery, 5(6), pp. 394-400. ISSN (print) 1570-1808

Stansfeld, Phillip, J., Grottesi, Alessandro, Sands, Zara, A., Sansom, Mark, S.P., Gedeck, Peter, Gosling, Martin, Stanfield, Peter, R., Mitcheson, John, S. and Sutcliffe, Michael, J. (2008) Insight into the mechanism of inactivation and pH sensitivity in potassium channels from molecular dynamics simulations. Biochemistry, 47(28), pp. 7414-7422. ISSN (print) 0006-2960

T

Tavazzi, S, Raimondo, L, Silvestri, L, Spearman, P, Camposeo, A, Polo, M and Pisignano, D (2008) Dielectric tensor of tetracene single crystals: the effect of anisotropy on polarized absorption and emission spectra. The Journal of Chemical Physics, 128(15), p. 154709. ISSN (print) 0021-9606

Tavazzi, Silvia, Foot, Peter Jonathan Samuel, Labate, Massimiliano, Miozzo, Luciano, O'Malley, Hugh, Papagni, Antonio, Silvestri, Leonardo and Spearman, Peter (2008) Optical properties of inorganic/organic semiconductor hetero-structures : quaterthiphene intercalated in cadmium chalcogenophosphate. In: 22nd General Conference of the Condensed Matter Division of the European Physical Society; 25 - 29 August 2008, Rome, Italy. (Unpublished)

Tesfa Hunie, Kibur (2008) Novel applications of chiral non-recemic propargyl alcohols for asymmetric intramolecular Nicholas reaction - synthesis and screening of novel benzopyrans. (PhD thesis), Kingston University, .

Tyrrell, Elizabeth, Tesfa, Kibur Hunie, Greenwood, Iain and Mann, Alistair (2008) The synthesis and biological evaluation of a range of novel functionalised benzopyrans as potential potassium channel activators. Bioorganic & Medicinal Chemistry Letters, 18(3), pp. 1237-1240. ISSN (print) 0960-894X

U

Ullah, Saif (2008) Electronic properties of ladder-structured oligomers and the fabrication of electronic devices. (PhD thesis), Kingston University, .

W

Waheed, A., Cartledge, T., Owen, C.P. and Ahmed, S. (2008) Novel inhibitors of oestrone sulphatase based on the derivatives of 4-aminophenol. In: British Pharmaceutical Conference; 7-9 Sept 2008, Manchester, UK. (Unpublished)

Williams, N.A. (2008) Compounds containing a Spiro Phosphorus Atom. In: Katritzky, A.R. , Ramsden, C.R. , Scriven, E.F.V. and Taylor, R.J.K., (eds.) Comprehensive Heterocyclic Chemistry III. london : Elseveir. pp. 1065-1126. 12 ISBN 9780080449920

Y

Yong, K.C., Foot, P.J.S., Morgan, H., Cook, S., Tinker, A.J. and Ahmed, Md Aris (2008) Electrically conductive epoxidised natural rubber-polyaniline dodecylbenzenesulfonate blends prepared by solution mixing. Journal of Rubber Research, 11(2), pp. 59-77. ISSN (print) 1511-1768

Z

Ziedan, Noha I., Kadri, Hachemi and Westwell, Andrew D. (2008) The development of pro-apoptotic cancer therapeutics. Mini-Reviews in Medicinal Chemistry, 8(7), pp. 711-718. ISSN (print) 1389-5575