Article

Kadri, Hachemi, Taher, Taher E., Xu, Qin, Sharif, Maria, Ashby, Elizabeth, Bryan, Richard T., Willcox, Benjamin E. and Mehellou, Youcef (2020) Aryloxy diester phosphonamidate prodrugs of phosphoantigens (ProPAgens) as potent activators of Vγ9/Vδ2 T-cell immune responses. Journal of Medicinal Chemistry, 63(19), pp. 11258-11270. ISSN (print) 0022-2623

Miccoli, Ageo, Dhiani, Binar A., Thornton, Peter J., Lambourne, Olivia A., James, Edward, Kadri, Hachemi and Mehellou, Youcef (2020) Aryloxy triester phosphoramidates as phosphoserine prodrugs : a proof of concept study. ChemMedChem, 15(8), pp. 671-674. ISSN (print) 1860-7179

AlAmri, Mubarak A., Kadri, Hachemi, Alderwick, Luke J., Jeeves, Mark and Mehellou, Youcef (2018) The photosensitising clinical agent verteporfin is an inhibitor of SPAK and OSR1 kinases. ChemBioChem, 19(19), pp. 2072-2080. ISSN (print) 1439-4227

Mehellou, Youcef, Alamri, Mubarak A., Dhiani, Binar A. and Kadri, Hachemi (2018) C-terminal phosphorylation of SPAK and OSR1 kinases promotes their binding and activation by the scaffolding protein MO25. Biochemical and Biophysical Research Communications, 503(3), pp. 1868-1873. ISSN (print) 0006-291X

Kadri, Hachemi, Lambourne, Olivia A. and Mehellou, Youcef (2018) Niclosamide : a drug with many (re)purposes. ChemMedChem, 13(11), pp. 1088-1091. ISSN (print) 1860-7179

Barini, Erica, Miccoli, Ageo, Tinarelli, Federico, Mulholland, Katie, Kadri, Hachemi, Khanim, Farhat, Stojanovski, Laste, Read, Kevin D., Burness, Kerry, Blow, Julian J., Mehellou, Youcef and Muqit, Miratul M. K. (2018) The anthelmintic drug niclosamide and its analogues activate the Parkinson's disease associated protein kinase PINK1. ChemBioChem, 19(5), pp. 425-429. ISSN (print) 1439-4227

Salim, Mahboob, Knowles, Timothy J, Baker, Alfie T., Davey, Martin S., Jeeves, Mark, Sridhar, Pooja, Wilkie, John, Willcox, Carrie R., Kadri, Hachemi, Taher, Taher E., Vantourout, Pierre, Hayday, Adrian, Mehellou, Youcef, Mohammed, Fiyaz and Willcox, Benjamin E. (2017) BTN3A1 discriminates γδ T cell phosphoantigens from nonantigenic small molecules via a conformational sensor in its B30.2 domain. ACS Chemical Biology, 12(10), pp. 2631-2643. ISSN (print) 1554-8929

AlAmri, Mubarak A., Kadri, Hachemi, Dhiani, Binar A., Mahmood, Shumail, Elzwawi, Abdulrahman and Mehellou, Youcef (2017) WNK signaling inhibitors as potential antihypertensive drugs. ChemMedChem, 12(20), pp. 1677-1686. ISSN (print) 1860-7179

AlAmri, Mubarak A., Kadri, Hachemi, Alderwick, Luke J., Simpkins, Nigel S. and Mehellou, Youcef (2017) Rafoxanide and closantel inhibit SPAK and OSR1 kinases by binding to a highly conserved allosteric site on their C-terminal domains. ChemMedChem, 12(9), pp. 639-645. ISSN (print) 1860-7179

Osgerby, Laura, Lai, Yu-Chiang, Thornton, Peter J., Amalfitano, Joseph, Le Duff, Cécile S., Jabeen, Iqra, Kadri, Hachemi, Miccoli, Ageo, Tucker, James H. R., Muqit, Miratul M. K. and Mehellou, Youcef (2017) Kinetin riboside and its ProTides activate the Parkinson's disease associated PTEN-induced putative kinase 1 (PINK1) independent of mitochondrial depolarization. Journal of Medicinal Chemistry, 60(8), pp. 3518-3524. ISSN (print) 0022-2623

Kadri, Hachemi, Alamri, Mubarak A., Navratilova, Iva H., Alderwick, Luke J., Simpkins, Nigel S. and Mehellou, Youcef (2017) Towards the development of small-molecule MO25 binders as potential indirect SPAK/OSR1 kinase inhibitors. ChemBioChem, 18(5), pp. 460-465. ISSN (print) 1439-4227

Thornton, Peter J., Kadri, Hachemi, Miccoli, Ageo and Mehellou, Youcef (2016) Nucleoside phosphate and phosphonate prodrug clinical candidates. Journal of Medicinal Chemistry, 59(23), pp. 10400-10410. ISSN (print) 0022-2623

Karaaslan, Cigdem, Kadri, Hachemi, Coban, Tulay, Suzen, Sibel and Westwell, Andrew D. (2013) Synthesis and antioxidant properties of substituted 2-phenyl-1H-indoles. Bioorganic & Medicinal Chemistry Letters, 23(9), pp. 2671-2674. ISSN (print) 0960-894X

Kadri, H., Dale, T.C., Ewan, K.B.R. and Westwell, A.D. (2008) The design, synthesis and antitumour evaluation of novel small molecule inhibitors of the Dishevelled PDZ domain. European Journal of Cancer Supplements, 6(12), p. 137. ISSN (print) 1359-6349

Aiello, Stefania, Wells, Geoffrey, Stone, Erica L., Kadri, Hachemi, Bazzi, Rana, Bell, David R., Stevens, Malcolm F. G., Matthews, Charles S., Bradshaw, Tracey D. and Westwell, Andrew D. (2008) Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648). Journal of Medicinal Chemistry, 51(16), pp. 5135-5139. ISSN (print) 0022-2623

Ziedan, Noha I., Kadri, Hachemi and Westwell, Andrew D. (2008) The development of pro-apoptotic cancer therapeutics. Mini-Reviews in Medicinal Chemistry, 8(7), pp. 711-718. ISSN (print) 1389-5575

Kadri, Hachemi, Matthews, Charles S., Bradshaw, Tracey D., Stevens, Malcolm F. G. and Westwell, Andrew D. (2008) Synthesis and antitumour evaluation of novel 2- phenylbenzimidazoles. Journal of Enzyme Inhibition and Medicinal Chemistry, 23(5), pp. 641-647. ISSN (print) 1475-6366