2006

Abdulkadir, Huria (2006) Synthesis of potential enzyme inhibitors in the treatment of hormone-dependent prostate cancer. (PhD thesis), Kingston University, .

Alany, R.G., Rades, T., Nicoll, J., Tucker, I.G. and Davies, N.M. (2006) W/O microemulsions for ocular delivery : evaluation of ocular irritation and precorneal retention. Journal of Controlled Release, 111(1-2), pp. 145-152. ISSN (print) 0168-3659

Archer, Roland Peter (2006) The synthesis and biological evaluation of novel derivatives from the hop component Humulone. (PhD thesis), Kingston University, .

Baciu, Magdalena, Sebai, Sarra C, Ces, Oscar, Mulet, Xavier, Clarke, James A., Shearman, Gemma C, Law, Robert V, Templer, Richard H, Plisson, Christophe, Parker, Christine A and Gee, Antony (2006) Degradative transport of cationic amphiphilic drugs across phospholipid bilayers. Philosophical Transactions of the Royal Society A, 364(1847), pp. 2597-2614. ISSN (print) 1364-503X

Birmili, Wolfram, Allen, Andrew G., Bary, Frederick and Harrison, Roy M. (2006) Trace metal concentrations and water solubility in size-fractionated atmospheric particles and influence of road traffic. Environmental Science & Technology (including News & Research Notes), 40(4), pp. 1144-1153. ISSN (print) 0013-936X

Brower, Jerry J. (2006) Preparation and characterization of structurally stable polycrystalline La[sub]0.7Ca[sub]0.3Mn[sub]03 and La[sub]0.7Ca[sup]0.3(Mn[sup](1-x)Fe[sub]x)[sub]03 samples. (PhD thesis), Kingston University, .

Bunt, Craig R. and Alany, Raid (2006) Metformin extended release : a view point. American Journal of Drug Delivery, 4(3), p. 187. ISSN (print) 1175-9038

Busquets, Rosa, Puignou, Lluis and Galceran, Maria Teresa (2006) Determination of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in hemoglobin using on-line coupling of restricted access material to liquid chromatography–mass spectrometry. Analytica Chimica Acta, 559, pp. 45-53.

Busquets, Rosa, Puignou, Lluis, Galceran, Maria Teresa and Skog, Kerstin (2006) Effect of red wine marinades on the formation of heterocyclic amines in fried chicken breast. Journal of Agricultural and Food Chemistry, 54(21), pp. 8376-8384. ISSN (print) 0021-8561

Davis, M. and Koenders, M.A. (2006) Oscillated densely packed granular media immersed in a fluid. In: 1st International Conference on Vibro-Impact Systems; 20 - 22 Jul 2006, Loughborough, U.K..

Dhanani, Sachin Paryantray (2006) Biochemical evaluation of potential enzyme inhibitors. (PhD thesis), Kingston University, .

Dutton, P. Leslie, Munro, Andrew, W., Scrutton, Nigel, S. and Sutcliffe, Michael, J. (2006) Introduction. Quantum catalysis in enzymes: Beyond the transition state theory paradigm. Philosophical Transactions of the Royal Society B: Biological Sciences, 361(1472), pp. 1293-1294. ISSN (print) 0962-8436

Gaymes, Terry J., Padua, Rose Ann, Pla, Marika, Orr, Steven, Omidvar, Nader, Chomienne, Christine, Mufti, Ghulam J. and Rassool, Feyruz V. (2006) Histone Deacetylase Inhibitors (HDI) cause DNA damage in leukemia cells : a mechanism for leukemia-specific HDI-dependent apoptosis? Molecular Cancer Research, 4(8), pp. 563-573. ISSN (print) 1541-7786

Georgiades, Savvas and Clardy, Jon (2006) Preparation of a Psammaplysene-Based Library. Organic Letters, 8(19), pp. 4251-4254. ISSN (print) 1523-7060

Hardy, Ines, Alany, Raid, Russell, Bruce and Hardy, Gill (2006) Antimicrobial effects of arginine and nitrogen oxides and their potential role in sepsis. Current Opinion in Clinical Nutrition and Metabolic Care, 9(3), pp. 225-232. ISSN (print) 1363-1950

Hilton, P.J., McKinnon, W., Lord, G.A., Peron, J.-M.R. and Forni, L.G. (2006) Unexplained acidosis of malnutrition: a study by ion-exchange chromatography/mass spectrometry. Biomedical Chromatography, 20(12), pp. 1386-1389. ISSN (print) 0269-3879

Karatholuvhu, Maheswaran, Sinclair, Alex, Newton, Annabella, Alcaraz, Marie-Lyne, Stockman, Robert and Fuchs, Philip (2006) A Concise Total Synthesis of DL-Histrionicotoxin. Journal of the American Chemical Society, 128(39), pp. 12656-12657. ISSN (print) 0002-7863

Lota, Rupinder K., Dhanani, Sachin, Owen, Caroline P. and Ahmed, Sabbir (2006) Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-hydroxyphenyl ketones as potential inhibitors of 17[beta]-hydroxysteroid dehydrogenase type 3 (17[beta]-HSD3). Bioorganic & Medicinal Chemistry Letters, 16(17), pp. 4519-4522. ISSN (print) 0960-894X

Mahale, Sachin, Aubry, Carine, Wilson, A. James, Jenkins, Paul, R., Maréchal, Jean-Didier, Sutcliffe, Michael, J. and Chaudhuri, Bhabatosh (2006) CA224, a non-planar analogue of fascaplysin, inhibits Cdk4 but not Cdk2 and arrests cells at G0/G1 inhibiting pRB phosphorylation. Bioorganic and Medicinal Chemistry Letters, 16(16), pp. 4272-4278. ISSN (print) 0960-894X

Mahale, Sachin, Aubry, Carine, Jenkins, Paul, R., Maréchal, Jean-Didier, Sutcliffe, Michael, J. and Chaudhuri, Bhabatosh (2006) Inhibition of cancer cell growth by cyclin dependent kinase 4 inhibitors synthesized based on the structure of fascaplysin. Bioorganic Chemistry, 34(5), pp. 287-297. ISSN (print) 0045-2068

Masgrau, Laura, Roujeinikova, Anna, Johannissen, Linus, O., Hothi, Parvinder, Basran, Jaswir, Ranaghan, Kara, E., Mulholland, Adrian, J., Sutcliffe, Michael, J., Scrutton, Nigel, S. and Leys, David (2006) Atomic description of an enzyme reaction dominated by proton tunneling. Science, 312(5771), pp. 237-241. ISSN (print) 0036-8075

McKinnon, William, Lord, Gwyn A, Forni, Lui G, Peron, Jean-Marie R and Hilton, Philip J (2006) A rapid LC-MS method for determination of plasma anion profiles of acidotic patients. Journal of Chromatography B, 833(2), pp. 179-185. ISSN (print) 1570-0232

McLean, Kirsty, Clift, Daniel, Lewis, Geraint, Sabri, Muna, Balding, Philip, R., Sutcliffe, Michael, J., Leys, David and Munro, Andrew, W. (2006) The preponderance of P450s in the Mycobacterium tuberculosis genome. Trends in Microbiology, 14(5), pp. 220-228. ISSN (print) 0966-842X

Millet, Julien (2006) Approaches towards a stereoselective Nicholas reaction. (PhD thesis), Kingston University, .

Owen, Caroline P, Dhanani, Sachin, Patel, Chirag H, Shahid, Imran and Ahmed, Sabbir (2006) Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17[alpha]-hydroxylase/17,20-lyase (P450[sub]17[alpha]). Bioorganic & Medicinal Chemistry Letters, 16(15), pp. 4011-4015. ISSN (print) 0960-894X

Patel, Chirag H., Dhanani, Sachin, Owen, Caroline P. and Ahmed, Sabbir (2006) Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of 4-substituted phenyl alkyl imidazole-based inhibitors of the enzyme complex 17[alpha]-hydroxylase/17,20-lyase (P450[sub]17[alpha]). Bioorganic & Medicinal Chemistry Letters, 16(18), pp. 4752-4756. ISSN (print) 0960-894X

Perry, Matthew, Stansfeld, Phillip, J., Leaney, Joanne, Wood, Claire, de Groot, Marcel, J., Leishman, Derek, Sutcliffe, Michael, J. and Mitcheson, John, S. (2006) Drug binding interactions in the inner cavity of hERG channels: Molecular insights from structure-activity relationships of clofilium and ibutilide analogs. Molecular Pharmacology, 69(2), pp. 509-519. ISSN (print) 0026-895X

Pudney, Christopher, R., Hay, Sam, Sutcliffe, Michael, J. and Scrutton, Nigel, S. (2006) α-secondary isotope effects as probes of "tunneling-ready" configurations in enzymatic H-tunneling: Insight from environmentally coupled tunneling models. Journal of the American Chemical Society, 128(43), pp. 14053-14058. ISSN (print) 0002-7863

Raimondo, L., Campione, M., Laicini, M., Moret, M., Sassella, A., Spearman, P. and Tavazzi, S. (2006) Absorbance spectra of polycrystalline samples and twinned crystals of oligothiophenes. Applied Surface Science, 253(1), pp. 271-274. ISSN (print) 0169-4332

Raimondo, L., Laicini, M., Spearman, P., Tavazzi, S. and Borghesi, A. (2006) Effect of static and dynamic disorder on exciton mobility in oligothiophenes. The Journal of Chemical Physics, 125(2), 024702. ISSN (print) 0021-9606

Scrutton, Nigel, S., Sutcliffe, Michael, J. and Dutton, P. Leslie (2006) Quantum catalysis in enzymes: Beyond the transition state theory paradigm. A Discussion Meeting held at the Royal Society on 14 and 15 November 2005. Journal of the Royal Society Interface, 3(8), pp. 465-469. ISSN (print) 1742-5689

Seddon, John M, Squires, Adam M, Conn, Charlotte E, Ces, Oscar, Heron, Andrew J, Mulet, Xavier, Shearman, Gemma C and Templer, Richard H (2006) Pressure-jump X-ray studies of liquid crystal transitions in lipids. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 364(1847), pp. 2635-2655. ISSN (print) 1364-503X

Shearman, G C, Ces, O, Templer, R H and Seddon, J M (2006) Inverse lyotropic phases of lipids and membrane curvature. Journal of Physics: Condensed Matter, 18(28), S1105-S1124. ISSN (print) 0953-8984

Sinclair, Alex, Arini, Louise, Rejzek, Martin, Szeto, Peter and Stockman, Robert (2006) Combining Two-Directional Synthesis and Tandem Reactions, Part 8: A Novel Condensation/Michael Addition/Cycloaddition/Fragmentation/Lactamisation Cascade. Synlett, 2006(14), pp. 2321-2324. ISSN (print) 0936-5214

Stansfeld, Phillip, J., Sutcliffe, Michael, J. and Mitcheson, John, S. (2006) Molecular mechanisms for drug interactions with hERG that cause long QT syndrome. Expert Opinion on Drug Metabolism and Toxicology, 2(1), pp. 81-94. ISSN (print) 1742-5255

Sutcliffe, Michael, J. and Scrutton, Nigel, S. (2006) Computational studies of enzyme mechanism: Linking theory with experiment in the analysis of enzymic H-tunnelling. Physical Chemistry Chemical Physics, 8(39), pp. 4510-4516. ISSN (print) 1463-9076

Sutcliffe, Michael, J., Masgrau, Laura, Roujeinikova, Anna, Johannissen, Linus, O., Hothi, Parvinder, Basran, Jaswir, Ranaghan, Kara, E., Mulholland, Adrian, J., Leys, David and Scrutton, Nigel, S. (2006) Hydrogen tunnelling in enzyme-catalysed H-transfer reactions: Flavoprotein and quinoprotein systems. Philosophical Transactions of the Royal Society B. Biological Sciences, 361(1472), pp. 1375-1386. ISSN (print) 0962-8436

Tavazzi, S., Laicini, M., Raimondo, L., Spearman, P., Borghesi, A., Papagni, A. and Trabattoni, S. (2006) Evidence of polarized charge-transfer transitions by probing the weak dielectric tensor components of oligothiophene crystals. Applied Surface Science, 253(1), pp. 296-299. ISSN (print) 0169-4332

Tavazzi, S., Campione, M., Laicini, M., Raimondo, L., Borghesi, A. and Spearman, P. (2006) Measured Davydov splitting in oligothiophene crystals. The Journal of Chemical Physics, 124(19), p. 194710. ISSN (print) 0021-9606

Tavazzi, S., Spearman, P., Silvestri, L., Raimondo, L., Camposeo, A. and Pisignano, D. (2006) Propagation properties and self-waveguided fluorescence emission in conjugated molecular solids. Organic Electronics, 7(6), pp. 561-567. ISSN (print) 1566-1199

Westwood, I. M., Kawamura, A., Fullam, E., Russell, A. J., Davies, S. G. and Sim, E. (2006) Structure and mechanism of arylamine N-acetyltransferases. Current Topics In Medicinal Chemistry, 6(15), pp. 1641-1654. ISSN (print) 1568-0266

Yu, Yinglei, Paine, Mark, J.I., Maréchal, Jean-Didier, Kemp, Carol, A., Ward, Clive, J., Brown, Simon, Sutcliffe, Michael, J., Roberts, Gordon, C.K., Rankin, Elaine, M. and Wolf, C. Roland (2006) In silico prediction of drug binding to CYP2D6: identification of a new metabolite of metoclopramide. Drug Metabolism and Disposition, 34(8), pp. 1386-1392. ISSN (print) 0090-9556

de Groot, Marcel, J., Kirton, Stewart, B. and Sutcliffe, Michael, J. (2006) In silico methods for predicting ligand binding determinants of crtochromes p450. Frontiers in Medicinal Chemistry, 3(1), pp. 615-652. ISSN (print) 1567-2042