Article

Fudger, Alex, Cakir, Okan M., Khan, Yousaf, Sinclair, Alex and Le Gresley, Adam (2022) Chemical synthesis of a library of natural product-like derivatives based on pinnaic acid and initial evaluation of their anti-cancer activity. Organic & Biomolecular Chemistry, 47(20), pp. 9408-9421. ISSN (print) 1477-0520

Malik, Samerah, Sinclair, Alex, Ryan, Ali and Le Gresley, Adam (2020) Synthesis and initial evaluation of a novel fluorophore for selective FMDV 3C Protease detection. Molecules, 25(16), p. 3599. ISSN (online) 1420-3049

Bywaters, Luke, Mulcahy-Ryan, Lauren, Fielder, Mark, Sinclair, Alex and Le Gresley, Adam (2017) Synthetic scale-up of a novel fluorescent probe and its biological evaluation for surface detection of 'Staphylococcus aureus'. Molecular and Cellular Probes, 36, pp. 1-9. ISSN (print) 0890-8508

Le Gresley, A, Gudivaka, V, Carrington, S, Sinclair, A and Brown, J E (2016) Synthesis, analysis and biological evaluation of novel indolquinonecryptolepine analogues as potential anti-tumour agents. Organic & Biomolecular Chemistry, 14, pp. 3069-3079. ISSN (print) 1477-0520

Le Gresley, Adam, Simpson, Emma, Sinclair, Alex, Williams, Neil, Burnett, Gary, Bradshaw, David and Lucas, Robert (2015) The application of high resolution diffusion NMR for the characterisation and quantification of small molecules in saliva/dentifrice slurries. Analytical Methods, 7(6), p. 2323. ISSN (print) 1759-9660

Sinclair, Alex, Mulcahy, Lauren, Geldeard, Lynsey, Malik, Samerah, Fielder, Mark and Le Gresley, Adam (2013) Development of an in situ culture-free screening test for the rapid detection of Staphylococcus aureus within healthcare environments. Organic & Biomolecular Chemistry, 11(20), pp. 3307-3313. ISSN (print) 1477-0520

Tyrrell, Elizabeth, Mazloumi, Khatebeh, Banti, Donatella, Sajdak, Paulina, Sinclair, Alex and Le Gresley, Adam (2012) The enantiospecific synthesis of chromanes and isochromanes using a variant of an intramolecular Nicholas reaction. Tetrahedron Letters, 53(33), pp. 4280-4282. ISSN (print) 0040-4039

Tyrrell, Elizabeth, Archer, Roland, Tucknott, Matt, Colston, Kay, Pirianov, Grisha, Ramanthan, Dharahana, Dhillon, Rajdeep, Sinclair, Alex and Skinner, G.A. (2012) The synthesis and anticancer effects of a range of natural and unnatural hop [beta]-acids on breast cancer cells. Phytochemistry Letters, 5(1), pp. 144-149. ISSN (print) 1874-3900

Gresley, Adam le, Kenny, Jackie, Cassar, Claire, Kelly, Alison, Sinclair, Alex and Fielder, Mark D (2012) The application of high resolution diffusion NMR to the analysis of manuka honey. Food Chemistry, 135(4), pp. 2879-86. ISSN (print) 0308-8146

Robbins, Diane, Newton, Annabella F., Gignoux, Camille, Legeay, Jean-Christophe, Sinclair, Alex, Rejzek, Martin, Laxon, Carly A., Yalamanchili, Sai K., Lewis, William, O'Connell, Maria A. and Stockman, Robert A. (2011) Synthesis of natural-product-like scaffolds in unprecedented efficiency via a 12-fold branching pathway. Chemical Science, 2(11), pp. 2232-2235. ISSN (print) 2041-6520

Le Gresley, Adam, Abdullah, Ammara, Chawla, Deepak, Desai, Pratchi, Ghosh, Uttam, Gollapalli, Uma, Kiran, Munazza, Lafon, Shehri and Sinclair, Alex (2011) Diacrylamides as selective G-quadruplex ligands in in vitro and in vivo assays. MedChemComm, 2(6), pp. 466-470. ISSN (print) 2040-2503

Aliev, Abil E., Sinclair, Alex J., Zhou, Shen, Wilden, John D., Caddick, Stephen, Kullmann, Dimitri M. and Rusakov, Dmitri A. (2009) Density functional and spectroscopic studies of nitrogen inversion in substituted dizocilpines. Journal of Physical Organic Chemistry, 22(6), pp. 607-612. ISSN (print) 0894-3230

Sinclair, Alex and Stockman, Robert (2007) Thirty-five years of synthetic studies directed towards the histrionicotoxin family of alkaloids. Natural Product Reports, 24(2), pp. 298-326. ISSN (print) 0265-0568

Sinclair, Alex, Arini, Louise, Rejzek, Martin, Szeto, Peter and Stockman, Robert (2006) Combining Two-Directional Synthesis and Tandem Reactions, Part 8: A Novel Condensation/Michael Addition/Cycloaddition/Fragmentation/Lactamisation Cascade. Synlett, 2006(14), pp. 2321-2324. ISSN (print) 0936-5214

Karatholuvhu, Maheswaran, Sinclair, Alex, Newton, Annabella, Alcaraz, Marie-Lyne, Stockman, Robert and Fuchs, Philip (2006) A Concise Total Synthesis of DL-Histrionicotoxin. Journal of the American Chemical Society, 128(39), pp. 12656-12657. ISSN (print) 0002-7863

Stockman, Robert, Sinclair, Alex, Arini, Louise, Szeto, Peter and Hughes, David (2004) A Two-Directional Synthesis of (+/-)-Perhydrohistrionicotoxin. The Journal of Organic Chemistry, 69(5), pp. 1598-1602. ISSN (print) 0022-3263

Arini, Louise, Sinclair, Alex, Szeto, Peter and Stockman, Robert (2004) Direct synthesis of aliphatic vinyl aziridines. Tetrahedron Letters, pp. 1589-1591.

Patent

Sinclair, Alex [Inventor], Fielder, Mark [Inventor] and Le Gresley, Adam [Inventor] (2013) Kingston University Higher Education Corporation Rhodamine based fluorescent probe for coagulase activity and detection of coagulase producing bacterial strains. WO 2014013272 A1.