Article

Ahmed, Sabbir, James, Karen and Patel, Chirag K. (2000) First report of the investigation into the importance of pK[sub]a in the inhibition of estrone sulfatase by sulfamate containing compounds. Biochemical and Biophysical Research Communications, 272(2), pp. 583-585. ISSN (print) 0006-291X

Ahmed, Sabbir and Amanuel, Yonas (2000) Synthesis and biochemical evaluation of novel inhibitors of aromatase (AR) using an enhanced representation of the active site of AR derived from the consideration of the reaction mechanism. Biochemical and Biophysical Research Communications, 267(1), pp. 356-361. ISSN (print) 0006-291X

Ahmed, Sabbir (2000) The use of the novel substrate-heme complex approach in the derivation of a representation of the active site of the enzyme cholesterol side chain cleavage. Biochemical and Biophysical Research Communications, 274(3), pp. 821-824. ISSN (print) 0006-291X

Ahmed, Sabbir (2000) The use of the substrate-heme complex approach in the design, synthesis, biochemical evaluation, and rationalization of the inhibitory activity of a range of azole compounds against cholesterol side chain cleavage enzyme. Biochemical and Biophysical Research Communications, 275(1), pp. 75-76. ISSN (print) 0006-291X

Alany, R.G, Rades, T, Agatonovic-Kustrin, S, Davies, N.M and Tucker, I.G (2000) Effects of alcohols and diols on the phase behaviour of quaternary systems. International Journal of Pharmaceutics, 196(2), pp. 141-145. ISSN (print) 0378-5173

Ashraf, Muhammed A., Jones, Keith and Handa, Sheetal (2000) Biomimetic ligands for transition metals: catechol-containing peptides. Bioorganic & Medicinal Chemistry Letters, 10(14), pp. 1617-1620. ISSN (print) 0960-894X

Banti, Donatella, Cicogna, Francesca, Di Bari, Lorenzo and Caporusso, Anna Maria (2000) Diastereoselectivity in the synthesis of bicyclic titanacyclopentenes from chiral 6-hepten-1-ynes. Tetrahedron Letters, 41(40), pp. 7773-7777. ISSN (print) 0040-4039

Basran, Jaswir, Chohan, Kamaldeep, K., Sutcliffe, Michael, J. and Scrutton, Nigel, S. (2000) Differential coupling through Val-344 and Tyr-442 of trimethylamine dehydrogenase in electron transfer reactions with ferricenium ions and electron transferring flavoprotein. Biochemistry, 39(31), pp. 9188-9200. ISSN (print) 0006-2960

Chohan, Kamaldeep, K., Wo, Galen, Oswald, Robert, E. and Sutcliffe, Michael, J. (2000) Structural insights into NMDA ionotropic glutamate receptors via molecular modelling. Journal of Molecular Modeling, 6(1), pp. 16-25. ISSN (print) 0949-183X

Escolano, Carmen and Jones, Keith (2000) Aryl radical cyclisation onto pyrroles: a divergent synthesis of spiropyrrolidinyloxindoles and pyrroloquinolines. Tetrahedron Letters, 41(46), pp. 8951-8955. ISSN (print) 0040-4039

Evans, S.J., Haines, P.J. and Skinner, G.A. (2000) Pyrolysis-gas-chromatographic study of a series of polyester thermosets. Journal of Analytical and Applied Pyrolysis, 55(1), pp. 13-28. ISSN (print) 0165-2370

Fiumana, Andrea and Jones, Keith (2000) Annulation of indole via indole radicals: addition of the 2-indolyl radical to aromatic rings. Tetrahedron Letters, 41(21), pp. 4209-4211. ISSN (print) 0040-4039

Fowler, Stephen, M., Riley, Robert, J., Pritchard, Michael, P., Sutcliffe, Michael, J., Friedberg, Thomas and Wolf, C. Roland (2000) Amino acid 305 determines catalytic center accessibility in CYP3A4. Biochemistry, 39(15), pp. 4406-4414. ISSN (print) 0006-2960

Garner, R.C., Barker, James, Flavell, C, Garner, J.V., Whattam, M, Young, G.C, Cussans, N, Jezequel, S and Leong, D (2000) A validation study comparing accelerator MS and liquid scintillation counting for analysis of ¹⁴C-labelled drugs in plasma, urine and faecal extract. Journal of Pharmaceutical and Biomedical Analysis, 24(2), pp. 197-209. ISSN (print) 0731-7085

Harris, Richard J., Meskys, Rolandas, Sutcliffe, Michael J. and Scrutton, Nigel S. (2000) Kinetic studies of the mechanism of carbon-hydrogen bond breakage by the heterotetrameric sarcosine oxidase of Arthrobacter sp. 1-IN. Biochemistry, 39(6), pp. 1189-1198. ISSN (print) 0006-2960

Hilton, Stephen T., Ho, Tim C. T., Pljevaljcic, Goran and Jones, Keith (2000) A new route to spirooxindoles. Organic Letters, 2(17), pp. 2639-2641. ISSN (print) 1523-7060

Jones, Keith and Storey, John M.D. (2000) Intramolecular organolithium addition to indol-2(3H)-ones; an approach to the synthesis of pyrrolo[1,2-a] indoles and pyrido[1,2-a] indoles. Journal of the Chemical Society: Perkin Transactions 1(5), pp. 769-774. ISSN (print) 0300-922X

Jones, Keith, Fiumana, Andrea and Escudero-Hernandez, Maria L (2000) Pyridine radicals in synthesis. Part 3: Cyclopentannulation of pyridine via the 3-pyridyl radical and a formal synthesis of (+/-)-oxerine. Tetrahedron, 56(3), pp. 397-406. ISSN (print) 0040-4020

Jones, Keith and Storey, John M.D. (2000) An aryl radical cyclisation approach to highly substituted oxindoles related to mitomycins. ARKIVOC : Archive for Organic Chemistry, 5, pp. 755-768. ISSN (print) 1424-6376

Jones, Matthew, Basran, Jaswir, Sutcliffe, Michael, J., Grossmann, J. Günter and Scrutton, Nigel, S. (2000) X-ray scattering studies of Methylophilus methylotrophus (sp. W3a1) electron-transferring flavoprotein: Evidence for multiple conformational states and an induced fit mechanism for assembly with trimethylamine dehydrogenase. The Journal of Biological Chemistry, 275(28), pp. 21349-21354. ISSN (print) 0021-9258

Kouki, Faycal, Spearman, Peter, Valat, Pierre, Horowitz, Gilles and Garnier, Francis (2000) Experimental determination of excitonic levels in [alpha]-oligothiophenes. The Journal of Chemical Physics, 113(1), pp. 385-391. ISSN (print) 0021-9606

Kresinski, Roman A., Platt, Andrew W. G. and Seddon, Joanne A. (2000) Lanthanide complexes with O[sub]2PH[sub]2, O[sub]2P(CH[sub]2Cl)[sub]2 and O[sub]2P(CH[sub]2OH)[sub]2 ligands: a solid-state tubular micelle. CrystEngComm (Crystal Engineering Communications), 2, pp. 177-182. ISSN (online) 1466-8033

Millar, Ross W., Colclough, M. Eamon, Claridge, Robert P., Hamid, Javid, Philbin, Simon and Chauhan, Naren (2000) ChemInform abstract : Clean synthesis of energetic materials using solid‐supported reactions and related technologies. ChemInform, 31(49), ISSN (print) 0931-7597

Mulholland, Dulcie A., Schwikkard, Sianne L., Sandor, Peter and Nuzillard, Jean M. (2000) Delevoyin C, a tetranortriterpenoid from Entandrophragma delevoyi. Phytochemistry, 53(4), pp. 465-468. ISSN (print) 0031-9422

Mulholland, Dulcie A., Randrianarivelojosia, Milijaona, Lavaud, Catherine, Nuzillard, Jean-Marc and Schwikkard, Sianne L. (2000) Limonoid derivatives from Astrotrichilia voamatata. Phytochemistry, 53(1), pp. 115-118. ISSN (print) 0031-9422

Reymann, S. and Koenders, C. (2000) Filter cake formation and volume-time curves in dead-end filtration. Chemical Engineering & Technology - CET, 23(6), pp. 501-504. ISSN (print) 0930-7516

Schwikkard, Sianne, Zhou, Bing-Nan, Glass, Thomas E., Sharp, Jessica L., Mattern, Michael R., Johnson, Randall K. and Kingston, David G. I. (2000) Bioactive Compounds from Combretum erythrophyllum. Journal of Natural Products, 63(7), pp. 1045-1046. ISSN (print) 0163-3864

Schwikkard, Sianne, Zhou, Bing-Nan, Glass, Thomas E., Sharp, Jessica L., Mattern, Michael R., Johnson, Randall K. and Kingston, David G. I. (2000) Bioactive Compounds from Combretum erythrophyllum. Journal of Natural Products, 63(4), pp. 457-460. ISSN (print) 0163-3864

Shah, Jatin, Brown, John W., Buckley-Dhoot, Eileen and Bandara, Asoka J. (2000) The use of a phenylpyrazine liquid crystalline material with a liquid crystalline solvent mediator as an ion-selective electrode. Journal of Materials Chemistry, 10(12), pp. 2627-2628. ISSN (print) 0959-9428

Storey, John M.D. (2000) A novel synthesis of spirocyclic pyrrolidin-2-ones. Tetrahedron Letters, 41(42), pp. 8173-8176. ISSN (print) 0040-4039

Sutcliffe, Michael, J. and Scrutton, Nigel, S. (2000) Enzyme catalysis: Over-the-barrier or through-the-barrier? Trends in Biochemical Sciences, 25(9), pp. 405-408. ISSN (print) 0968-0004

Sutcliffe, Michael, J. and Scrutton, Nigel, S. (2000) Enzymology takes a quantum leap forward. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 358(1766), pp. 367-386. ISSN (print) 1364-503X

Thompson, G.A., Leyland, M.L., Ashmole, I., Sutcliffe, M.J. and Stanfield, P.R. (2000) Residues beyond the selectivity filter of the K+ channel Kir2.1 regulate permeation and block by external Rb+ and Cs+. Journal of Physiology, 526(2), pp. 231-240. ISSN (print) 0022-3751

Trickey, Peter, Basran, Jaswir, Lian, Lu-Yun, Chen, Zhi-Wei, Barton, John, D., Sutcliffe, Michael, J., Scrutton, Nigel, S. and Matthews, F. Scott (2000) Structural and biochemical characterization of recombinant wild type and a C30A mutant of Trimethylamine dehydrogenase from Methylophilus methylotrophus (sp. W3A1). Biochemistry, 39(26), pp. 7678-7688. ISSN (print) 0006-2960

Troisi, G. M. and Mason, C. F. (2000) PCB-associated alteration of hepatic steroid metabolism in harbor seals ('Phoca vitulina'). Journal of Toxicology and Environmental Health - Part A Current Issues, 61(8), pp. 649-655. ISSN (print) 1528-7394

Book Section

Scrutton, Nigel S. and Sutcliffe, Michael J. (2000) Trimethylamine dehydrogenase and electron transferring flavoprotein. In: Holzenburg, Andreas and Scrutton, Nigel S., (eds.) Enzyme-Catalyzed Electron and Radical Transfer. Springer US. pp. 145-181. (Subcellular Biochemistry, (35)) ISBN 9780306463990

Conference or Workshop Item

Millar, Ross, Colclough, Eamon, Claridge, Robert, Hamid, Javid, Philbin, Simon and Chauhan, Naren (2000) Clean synthesis of energetic materials using solid-supported reactions and related technologies. In: 31st International Annual Conference of Institut für Chemische Technologie (ICT); 27-30 Jun 2000, Karlsruhe, Germany. (Unpublished)

Philbin, Simon (2000) Current strands of research in DERA on the chemistry of energetic materials and insensitive munitions. In: National Defense Industrial Association (NDIA) Annual Conference on Insensitive Munitions and Energetic Materials (IM/EM) Technology; 27-30 Nov 2000, San Antonio, U.S.A.. (Unpublished)

Patent

Foot, Peter J S [Inventor], Singer, Richard [Inventor], Sugrue, Maria [Inventor] and Youngs, Ian J [Inventor] (2000) The Secretary of State for Defence Sol-gel route to transparent metal oxide films. US6074471.

Thesis

Amanuel, Y. (2000) Design, synthesis and biochemical evaluation of inhibitors of aromatase. (MPhil thesis), Kingston University, .

Jagroop, I. Anita (2000) The effect of various drugs and agonists on human platelet shape change. (MPhil thesis), Kingston University, .

James, Karen Elizabeth (2000) Synthesis and biochemical evaluation of inhibitors of estrone sulfatase. (PhD thesis), Kingston University, .

Miah, Mijan (2000) The high frequency electromagnetic properties of conducting polymers. (PhD thesis), Kingston University, .

Poussin, Denis (2000) Synthesis stability and properties of processible conducting polymers. (PhD thesis), Kingston University, .

Sampson, Luther (2000) Attempted synthesis and biochemical evaluation of non-steroidal estrone sulfatase inhibitors. (MPhil thesis), Kingston University, .

Shah, Jatin (2000) Novel liquid crystalline materials for potentiometric analysis. (PhD thesis), Kingston University, .

Sugrue, Maria (2000) Sol-Gel routes to transparent conductive coatings. (PhD thesis), Kingston University, .