A new route to spirooxindoles

Hilton, Stephen T., Ho, Tim C. T., Pljevaljcic, Goran and Jones, Keith (2000) A new route to spirooxindoles. Organic Letters, 2(17), pp. 2639-2641. ISSN (print) 1523-7060


Reaction of indole amides 5 with tributylstannane gave spiroindolenines 9 which are readily converted into spiropyrrolidinyloxindoles. This tricyclic system is found in a number of interesting natural products.

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