Ziedan, Noha I., Kadri, Hachemi and Westwell, Andrew D. (2008) The development of pro-apoptotic cancer therapeutics. Mini-Reviews in Medicinal Chemistry, 8(7), pp. 711-718. ISSN (print) 1389-5575

Abstract

Resistance to apoptosis is one of the fundamental hallmarks of cancer. Recently, the selective induction of apoptosis in cancer cells has emerged as an exciting possibility for the development of future selective cancer therapy. This review will summarise the development of the major classes of small molecule "pro-apoptotic" antitumour agents.

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