Antagonistic activity of a consortium of strains 'Lactobacillus fermentum' ВКМ В-2793D and 'Lactobacillus reuteri' ВКМ В-3144D isolated from human milk to mastitis-inductioning pathogens.

Karlyshev, Andrey (2018) Antagonistic activity of a consortium of strains 'Lactobacillus fermentum' ВКМ В-2793D and 'Lactobacillus reuteri' ВКМ В-3144D isolated from human milk to mastitis-inductioning pathogens. Biomedicine, 3, pp. 46-54. ISSN (print) 2074-5982

Official URL: https://elibrary.ru/item.asp?id=36237068

Abstract

The aim of the study was to study the antagonistic activity of strains of Lactobacillus fermentum BKM B-2793D, Lactobacillus reuteri BKM B-3144D isolated from human breast milk and their consortium to pathogens that cause mastitis during the lactation period. The lactobacilli and their consortium reveal antimicrobial activity against the indicator microorganisms used in this study including pathogens resistant to antibiotics. The consortium protects human mammary gland MCF-7 cells against adhesion and colonization by Staphylococcus aureus 8325-4. The obtained results suggest that lactobacilli from breast milk of healthy woman L. fermentum ВКМ В-2793D and L. reuteri ВКМ В-3144D and their consortium are excellent candidates for the development of probiotic preparation for prophylactics and treatment of lactational mastitis.

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