Sinclair, Alex, Arini, Louise, Rejzek, Martin, Szeto, Peter and Stockman, Robert (2006) Combining Two-Directional Synthesis and Tandem Reactions, Part 8: A Novel Condensation/Michael Addition/Cycloaddition/Fragmentation/Lactamisation Cascade. Synlett, 2006(14), pp. 2321-2324. ISSN (print) 0936-5214

Abstract

A tandem oxime formation/Michael addition/1,4-prototopic shift/[3+2]-cycloaddition of an acyclic symmetrical precursor results in a tricyclic isooxazolidine which then undergoes a further fragmentation/lactamisation cascade to generate a non-symmetrical tricyclic a-ketolactam as a single diastereomer

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Official URL:	http://dx.doi.org/10.1055/s-2006-949634
Item Type:	Article
Research Area:	Research Areas > Chemistry
Faculty, School or Research Centre:	Faculty of Science (until 2011) Faculty of Science, Engineering and Computing (until 2017) > School of Pharmacy and Chemistry
Date Deposited:	07 Feb 2012 11:23
Last Modified:	06 Oct 2020 13:58
DOI:	https://doi.org/10.1055/s-2006-949634
URI:	https://eprints.kingston.ac.uk/id/eprint/17357

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