The Campylobacter jejuni glycome

Karlyshev, Andrey V., Ketley, Julian M. and Wren, Brendan W. (2005) The Campylobacter jejuni glycome. FEMS microbiology reviews, 29(2), pp. 377-390. ISSN (print) 0168-6445

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Abstract

Microbial cell surface glycans in the form of glycolipids and glycoproteins frequently play important roles in cell-cell interaction and host immune responses. Given the likely importance of these surface structures in the survival and pathogenesis of Campylobacter jejuni, a concerted effort has been made to characterise these determinants genetically and structurally since the genome was sequenced in 2000. We review the considerable progress made in characterising the Campylobacter glycome including the lipooligosaccharide (LOS), the capsule and O- and N-linked protein glycosylation systems, and speculate on the roles played by glycan surface structures in the life-cycle of C. jejuni.

Item Type: Article
Research Area: Biological sciences
Faculty, School or Research Centre: Faculty of Science (until 2011) > School of Life Sciences
Depositing User: Andrey Karlyshev
Date Deposited: 16 Jan 2009 14:17
Last Modified: 16 Jan 2009 14:17
URI: http://eprints.kingston.ac.uk/id/eprint/4446

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