Shakespeare, Royce, Rudnicka, Alicja R., Welikala, Roshan, Barman, Sarah A., Khawaja, Anthony P., Foster, Paul J., Owen, Christopher G. and UK Biobank Eye and Vision Consortium (2025) Retinal vasculometry associations with cognition status in UK Biobank. Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring, 17, e270087. ISSN (online) 2352-8729
Abstract
Retinal vasculometry (RV) provides a neurovascular biomarker which may relate to cognitive status. However, the presence and form of association remains unclear and unexamined at scale. One hundred ten thousand two hundred eighty-two retinal images from 63,165 (95%) participants (mean age 56.6 years, 55.5% female) were analyzed. A one SD increase in cognition score was strongly associated with increased arteriolar width, arteriolar tortuosity, increased venular width particularly among those < 50 years and venular area among those > 50 years; also, inversely associated with venular tortuosity, and arteriolar and venular width variance.
Actions (Repository Editors)
 |
Item Control Page |