Bower-Cargill, Cherie, Yarandi, Niousha and Petróczi, Andrea (2022) A systematic review of the versatile effects of the Peruvian Maca Root (Lepidium meyenii) on sexual dysfunction, menopausal symptoms and related conditions. Phytomedicine Plus, 2(4), p. 100326. ISSN (online) 2667-0313
Abstract
The Lepidium meyenii plant also known as Peruvian Maca, originates from high altitudes in the Andes, it has a high nutritional content and is extensively used as an herbal supplement for conditions such as sexual dysfunction, semen quality and menopausal symptoms. This systematic review was conducted to assess the effects of Maca on variety of conditions and not limited to sexual dysfunction, semen quality and menopausal symptoms. An extensive systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2015. Three databases (PubMed, Science Direct and Google Scholar) in addition to patents were searched up to March 2021. The key criteria for inclusion were; (1) in vivo study (2) randomized controlled clinical trial; (3) subjects were given Maca regardless of the type, preparation and/or administration route; and (4) measurable clinical data on a physiological and/or psychological aspect were reported. Studies were categorised into human and animal model studies and were further grouped by the type and preparation of Maca, dose, duration and condition assessed. The studies were also assessed for risk of bias according to the Cochrane Collaborations tool. Studies were compared to ascertain whether a meta-analysis was feasible.
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