B148: Optimising Ambulatory Chemotherapy Services: A System for Monitoring Drug Delivery in Elastomeric Pumps

Salman, Dahlia, Gomes, Bruna, Di Paolo, Angela, Wertheim, David, Keyyali, Reem and Nabhani-Gebara, Shereen (2015) B148: Optimising Ambulatory Chemotherapy Services: A System for Monitoring Drug Delivery in Elastomeric Pumps. In: NCRI Cancer Conference 2015; 03 Nov 2015, Kingston University, London, UK. (Unpublished)

Abstract

Ambulatory Chemotherapy (AC), using small portable elastomeric pumps, allows patients to receive chemotherapy outside the hospital. AC services have positively impacted patients quality of life, satisfaction, staff workload and NHS costs [1-2]. Despite those advantages, accuracy and reliability of elastomeric pumps have been a limiting factor associated with adoption of AC [3]. A recent two-phase audit, carried out by the authors at three gastrointestinal medical day units, showed that in 40% of disconnection cases flow was lower than expected with some patients arriving at hospital prior to complete delivery of the chemotherapy dose. 58% of these cases had an estimated volume remaining which exceeded 10mL (total infusion volume=120mL). Inaccurate flow and infusion duration could result in unpredictable end of infusion time and affect patient safety, treatment efficacy and patient outcome (if pumps are disconnected before the full dose has been infused). An automated elastomeric pump monitoring system may thus help to predict end of infusion time. The aim of this study was to develop image analysis software for monitoring elastomeric pump performance.

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