A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation

Oliver, Catherine F., Modi, Sandeep, Sutcliffe, Michael J., Primrose, William U., Lian, Lu-Yun and Roberts, Gordon C.K. (1997) A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation. Biochemistry, 36(7), pp. 1567-1572. ISSN (print) 0006-2960

Official URL: http://dx.doi.org/10.1021/bi962826c

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