Specific genetic features of 'Campylobacter jejuni' strain G1 revealed by genome sequencing

Karlyshev, Andrey, Lehri, Burhan and Vieira, Ana (2015) Specific genetic features of 'Campylobacter jejuni' strain G1 revealed by genome sequencing. FEMS Microbiology Letters, 362(4), pp. 1-3. ISSN (print) 0378-1097

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This report describes a draft genome sequence of Campylobacter jejuni strain G1. The strain contains no plasmids, despite being resistant to tetracycline (Tet). Comparison of the genome of this strain with that of a reference strain NCTC 11168 (Tet sensitive) revealed the presence of a candidate gene that may be responsible for antibiotic resistance, as well as the genes involved in the synthesis of ganglioside-mimicking molecules responsible for the development of a neurodegenerative disorder, Guillain-Barré syndrome.

Item Type: Article
Uncontrolled Keywords: tetracycline resistance, multidrug efflux pump, lipo-oligosaccharide, Guillaine-Barre syndrome, ganglioside mimicry
Research Area: Allied health professions and studies
Biological sciences
Infection and immunology
Faculty, School or Research Centre: Faculty of Science, Engineering and Computing (until 2017) > School of Life Sciences
Related URLs:
Depositing User: Andrey Karlyshev
Date Deposited: 20 Jan 2015 09:19
Last Modified: 14 Aug 2015 15:18
DOI: https://doi.org/10.1093/femsle/fnu064
URI: http://eprints.kingston.ac.uk/id/eprint/30071

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