Use of C. Elegans as a model organism for sensing the effects of ELF-EMFs

Lacchini, A.H., Everington, M.L., Augousti, A.T. and Walker, A.J. (2007) Use of C. Elegans as a model organism for sensing the effects of ELF-EMFs. Journal of Physics: Conference Series, 76, 012027. ISSN (online) 1742-6596

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Abstract

For the past two decades, there have been concerns and controversy about the effects on human health of the increased exposure to extremely-low-frequency (ELF) electromagnetic fields (EMFs) resulting from electrification, in both residential and industrial settings. Several epidemiological studies have implicated ELF-EMFs averaging 0.4 μmUTesla (T) or more in increased risk of cancer, especially childhood leukaemia ; there have also been many reports demonstrating effects of power-frequency EMFs on cells. Unfortunately, however, the precise mechanisms by which ELF-EMFs exert biological effects have proven difficult to define and results of various studies have often been hard to reproduce. We believe that C. elegans offers an exciting opportunity to elucidate the effects of power-frequency EMFs on cell signalling pathways within the whole organism and are therefore investigating the effects of ELF-EMF exposure on MAPK signalling in intact worms and fertilized embryos. Through taking a targeted approach to studying the effects of ELF-EMF's on MAPK signalling in C. elegans we aim to gather data that is physiologically relevant. Presently, this research is at a preliminary stage of preparation, and more detailed results on the exposure of Caenorhabditis elegans to ELF-EMF radiation will be presented at the conference itself.

Item Type: Article
Additional Information: Paper presented at: Sensors and their Applications XIV 11–13 September 2007, Liverpool John Moores University, Liverpool, UK
Research Area: Physics
Faculty, School or Research Centre: Faculty of Science (until 2011) > School of Life Sciences
Faculty of Science (until 2011)
Depositing User: Katrina Clifford
Date Deposited: 29 May 2008
Last Modified: 27 Nov 2009 10:20
URI: http://eprints.kingston.ac.uk/id/eprint/3089

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