Polymorphisms in the apolipoprotein L1 gene and their effects on blood lipid and glucose levels in middle age males.

Page, Nigel, Olano-Martin, Estibaliz, Lanaway, Christopher, Turner, Rufus and Minihane, Anne Marie (2006) Polymorphisms in the apolipoprotein L1 gene and their effects on blood lipid and glucose levels in middle age males. Genes and Nutrition, 1(2), pp. 133-136. ISSN (print) 1555-8932

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Abstract

Apolipoprotein L1 in plasma is associated with high-density lipoprotein. Novel APOL1 polymorphisms are investigated along with the association of two common haplotypes (Lysl66Glu, Ile244Met, Lys271Arg) with circulating lipid and glucose levels. Although the amino acid substitutions occur in the amphipathic alpha helices region involved in lipid binding, these substitutions were found not to independently account for variability in circulating lipid and glucose levels in 149 middle age males.

Item Type: Article
Research Area: Biological sciences
Faculty, School or Research Centre: Faculty of Science (until 2011) > School of Life Sciences
Faculty of Science (until 2011)
Related URLs:
Depositing User: Nigel Page
Date Deposited: 22 Nov 2011 16:15
Last Modified: 22 Nov 2011 16:15
URI: http://eprints.kingston.ac.uk/id/eprint/21689

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