Shahid, Imran, Patel, Chirag H., Dhanani, Sachin, Owen, Caroline P. and Ahmed, Sabbir (2008) Synthesis, biochemical evaluation of a range of potent 4-substituted phenyl alkyl imidazole-based inhibitors of the enzyme complex 17[alpha]-Hydroxylase/17,20-Lyase (P450[sub]17[alpha]). The Journal of Steroid Biochemistry and Molecular Biology, 110(1-2), pp. 18-29. ISSN (print) 0960-0760

Owen, Caroline, Dhanani, Sachin, Patel, Chirag and Ahmed, Sabbir (2007) Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-substituted phenyl alkyl triazole-based compounds as potential inhibitors of 17 alpha-hydroxylase/17,20-lyase (P450(17 alpha)). Letters in Drug Design and Discovery, 4(7), pp. 479-483. ISSN (print) 1570-1808

Owen, Caroline, Patel, Mijal, Patel, Chirag, Cartledge, Tim and Ahmed, Sabbir (2007) Synthesis and in vitro biochemical evaluation of a series of compounds as potential inhibitors of estrone sulfatase (ES) and the role of pK(a) in both the synthesis and the inhibitory activity of the potential inhibitors. Letters in Drug Design and Discovery, 4(6), pp. 394-398. ISSN (print) 1570-1808

Owen, Caroline, Patel, Chirag, Cartledge, Tim and Ahmed, Sabbir (2007) Synthesis and in vitro biochemical evaluation of a series of cycloalkyl esters of 4-sulfamoylated benzoic acid as inhibitors of estrone sulfatase (ES). Letters in Drug Design and Discovery, 4(6), pp. 399-403. ISSN (print) 1570-1808

Patel, Chirag H., Dhanani, Sachin, Owen, Caroline P. and Ahmed, Sabbir (2006) Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of 4-substituted phenyl alkyl imidazole-based inhibitors of the enzyme complex 17[alpha]-hydroxylase/17,20-lyase (P450[sub]17[alpha]). Bioorganic & Medicinal Chemistry Letters, 16(18), pp. 4752-4756. ISSN (print) 0960-894X

Owen, Caroline P, Dhanani, Sachin, Patel, Chirag H, Shahid, Imran and Ahmed, Sabbir (2006) Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17[alpha]-hydroxylase/17,20-lyase (P450[sub]17[alpha]). Bioorganic & Medicinal Chemistry Letters, 16(15), pp. 4011-4015. ISSN (print) 0960-894X

Patel, Chirag K., Owen, Caroline P. and Ahmed, Sabbir (2004) Inhibition of estrone sulfatase (ES) by alkyl and cycloalkyl ester derivatives of 4-[(aminosulfonyl)oxy] benzoic acid. Bioorganic & Medicinal Chemistry Letters, 14(3), pp. 605-609. ISSN (print) 0960-894X

Patel, Chirag K., Owen, Caroline P. and Ahmed, Sabbir (2003) The design, synthesis, and in vitro biochemical evaluation of a series of esters of 4-[(aminosulfonyl)oxy]benzoate as novel and highly potent inhibitors of estrone sulfatase. Biochemical and Biophysical Research Communications, 307(4), pp. 778-781. ISSN (print) 0006-291X

Patel, C.K., Galisson, A., James, K., Owen, C.P. and Ahmed, S. (2003) Structure-activity relationship determination within a group of substituted phenyl sulfamate based compounds against the enzyme oestrone sulfatase. Journal of Pharmacy and Pharmacology, 55(2), pp. 211-218. ISSN (print) 0022-3573

Ahmed, Sabbir, James, Karen, Owen, Caroline P. and Patel, Chirag K. (2002) Design, synthesis and biochemical evaluation of AC ring mimics as novel inhibitors of the enzyme estrone sulfatase (ES). Bioorganic & Medicinal Chemistry Letters, 12(10), pp. 1343-1346. ISSN (print) 0960-894X

Ahmed, Sabbir, James, Karen, Owen, Caroline P., Patel, Chirag K. and Sampson, Luther (2002) The mechanism of the irreversible inhibition of estrone sulfatase (ES) through the consideration of a range of methane- and amino-sulfonate-based compounds. Bioorganic & Medicinal Chemistry Letters, 12(9), pp. 1279-1282. ISSN (print) 0960-894X

Ahmed, Sabbir, Owen, Caroline P., James, Karen, Patel, Chirag K. and Sampson, Luther (2002) Evidence for the mechanism of the irreversible inhibition of oestrone sulphatase (ES) by aminosulphonate based compounds. The Journal of Steroid Biochemistry and Molecular Biology, 80(4-5), pp. 429-440. ISSN (print) 0960-0760

Ahmed, Sabbir, James, Karen, Owen, Caroline P. and Patel, Chirag K. (2002) Synthesis and biochemical evaluation of novel and potent inhibitors of the enzyme oestrone sulphatase (ES). The Journal of Steroid Biochemistry and Molecular Biology, 80(4-5), pp. 419-427. ISSN (print) 0960-0760

Ahmed, S., Owen, C.P., James, K., Sampson, L. and Patel, C.K. (2002) Review of estrone sulfatase and its inhibitors: an important new target against hormone dependent breast cancer. Current medicinal chemistry, 9(2), pp. 263-273. ISSN (print) 0929-8673

Ahmed, Sabbir, James, Karen, Owen, Caroline P., Patel, Chirag K. and Patel, Mijal B. (2001) Determination and use of a transition state for the enzyme estrone sulfatase (ES) from a proposed reaction mechanism. Bioorganic & Medicinal Chemistry Letters, 11(23), pp. 3001-3005. ISSN (print) 0960-894X

Ahmed, Sabbir, James, Karen, Owen, Caroline P., Patel, Chirag and Patel, Mijal (2001) Hydrophobicity, a physicochemical factor in the inhibition of the enzyme estrone sulfatase (ES). Bioorganic & Medicinal Chemistry Letters, 11(18), pp. 2525-2528. ISSN (print) 0960-894X

Ahmed, Sabbir, Owen, Caroline P., James, Karen, Patel, Chirag K. and Patel, Mijal (2001) Acid dissociation constant, a potential physicochemical factor in the inhibition of the enzyme estrone sulfatase (ES). Bioorganic & Medicinal Chemistry Letters, 11(7), pp. 899-902. ISSN (print) 0960-894X

Ahmed, Sabbir, James, Karen, Owen, Caroline P., Patel, Chirag and Patel, Mijal (2001) Novel inhibitors of the enzyme estrone sulfatase (ES). Bioorganic & Medicinal Chemistry Letters, 11(6), pp. 841-844. ISSN (print) 0960-894X

Ahmed, Sabbir, James, Karen and Patel, Chirag K. (2000) First report of the investigation into the importance of pK[sub]a in the inhibition of estrone sulfatase by sulfamate containing compounds. Biochemical and Biophysical Research Communications, 272(2), pp. 583-585. ISSN (print) 0006-291X