S-белок пробиотического штамма Lactobacillus crispatus 2029 предотвращает рост проницаемости монослоя Caco-2 энтероцитов человека, индуцируемый возбудителями кишечных инфекций = S-protein of the probiotic strain lactobacillus crispatus 2029 prevents the growth of permeability of the Caco-2 monolayer of human enterocytes induced by intestinal infections

Kosarev, Igor V., Vasilenko, Raisa N., Abramov, Vyacheslav M., Sakulin, Vadim K., Khlebnikov, Valentin S., Pchelintsev, Sergey Yu., Machulin, Andrey V., Abashina, Tatiana N., Samoilenko, Vladimir A., Uversky, Vladimir N. and Karlyshev, Andrey V. (2021) S-белок пробиотического штамма Lactobacillus crispatus 2029 предотвращает рост проницаемости монослоя Caco-2 энтероцитов человека, индуцируемый возбудителями кишечных инфекций = S-protein of the probiotic strain lactobacillus crispatus 2029 prevents the growth of permeability of the Caco-2 monolayer of human enterocytes induced by intestinal infections. Journal Biomed, 17(3), pp. 79-83. ISSN (print) 2074-5982

Abstract

The use of a biomodel of the confluent monolayer Caco-2 of enterocytes allowed us to reveal the ability of the S-protein isolated from strain LC2029 to prevent permeability disorders resulting from intestinal infections induced by pathogens (E. coli O157: H7, C. jejuni ATCC 33291, S. enteritidis ATCC 25928). This is important for maintaining the efficiency of the intestinal barrier.

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