Platelet monoamine oxidase B activity in Parkinson's disease: a re-evaluation

Jarman, J., Glover, V., Sandler, M., Turjanski, N. and Stern, G. (1993) Platelet monoamine oxidase B activity in Parkinson's disease: a re-evaluation. Journal of Neural Transmission. Parkinson's Disease and Dementia Section, 5(1), pp. 1-4. ISSN (print) 0936-3076

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An increase in platelet monoamine oxidase (MAO) B activity in drug-free parkinsonians (n = 6) compared with healthy controls (n = 10) has been confirmed using both phenylethylamine (PEA) and dopamine as substrates, reaching statistical significance in the case of PEA oxidising activity (p < 0.05). Thus, certain reports of raised platelet MAO B activity towards PEA but decreased activity towards dopamine in parkinsonians, raising the possibility of the existence of an abnormal form of MAO B in this condition, cannot be supported.

Item Type: Article
Research Area: Biological sciences
Infection and immunology
Faculty, School or Research Centre: Faculty of Science (until 2011) > School of Life Sciences
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Depositing User: Automatic Import Agent
Date Deposited: 30 Mar 2010 12:48
Last Modified: 30 Mar 2010 12:48

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