Mapping of the diabetes polygene Idd3 on mouse Chromosome 3 using novel congenic strains

Lord, C. J., Bohlander, S. K., Hopes, E. A., Montague, C. T., Hill, N. J., Prins, J.-B., Peterson, L. B., Wicker, L. S., Todd, J. A. and Denny, P. (1995) Mapping of the diabetes polygene Idd3 on mouse Chromosome 3 using novel congenic strains. Mammalian Genome, 6(9), pp. 563-570. ISSN (print) 0938-8990

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Abstract

Development of novel congenic mouse strains has allowed us to better define the location of the diabetogenic locus, Idd3, on Chromosome (Chr) 3. Congenic strains were identified by use of published and newly developed microsatellite markers, their genomes fingerprinted by a rapid, fluorescence-based approach, and their susceptibility to type 1 diabetes evaluated. The maximum interval containing Idd3 is now approximately 4 cM.

Item Type: Article
Research Area: Allied health professions and studies
Biological sciences
Pre-clinical and human biological sciences
Faculty, School or Research Centre: Faculty of Science (until 2011) > School of Life Sciences
Related URLs:
Depositing User: Natasha Hill
Date Deposited: 05 Nov 2018 11:27
Last Modified: 05 Nov 2018 15:15
DOI: https://doi.org/10.1007/BF00352359
URI: http://eprints.kingston.ac.uk/id/eprint/42238

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