HLA-DRB1*15 and pediatric aplastic anemia

Oguz, FS, Yalman, N, Diler, AS, Oguz, R, Anak, S and Dorak, MT (2002) HLA-DRB1*15 and pediatric aplastic anemia. Haematologica, 87(7), pp. 772-774. ISSN (print) 0390-6078

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Abstract

We report a positive association between HLA-DRB1*15 (p= 0.0002) in Turkish patients with pediatric severe aplastic anemia (SAA) and a paradoxically favorable influence of the susceptibility marker on the clinical response to immunosuppressive therapy. These findings point to an immune mechanism mediated by DRB1*15 in SAA which confers responsiveness to treatment.

Item Type: Article
Research Area: Biological sciences
Other laboratory based clinical subjects
Pre-clinical and human biological sciences
Faculty, School or Research Centre: Faculty of Science, Engineering and Computing (until 2017) > School of Life Sciences
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Depositing User: Kevin Hiscox
Date Deposited: 28 Sep 2018 10:39
Last Modified: 28 Sep 2018 10:39
URI: http://eprints.kingston.ac.uk/id/eprint/39684

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