Mutagenic heterocyclic amine content in thermally processed offal products

Khan, M.R, Betus, Laura, Busquets, Rosa and Puignou, Lluís (2009) Mutagenic heterocyclic amine content in thermally processed offal products. Food Chemistry, 112(4), pp. 838-843. ISSN (print) 0308-8146

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Heterocyclic amines (HAs) are potent mutagens formed during heat-processing of proteinaceous food. PhIP is the most ubiquitous and abundant mutagenic HA. In this study several offal products (beef liver, lamb kidney and beef tongue) have been thermally processed and analysed for HAs for the first time. Norharman and harman were the amines most abundant, found at concentrations below 2 ng g−1. PhIP was only formed up to 0.12 ng g−1. Among the rest of HAs analysed, only DMIP, MeIQx and 4,8-DiMeIQx were detectable in cooked kidney and tongue up to 0.25 ng g−1. The influence of cooking additives on HAs formation was evaluated, finding higher levels of norharman and harman, up to 8.87 ng g−1, in liver processed with additives, whereas similar levels of the rest of HAs were found in these samples. The low amounts of HAs found after the prolonged thermal treatments over 200 °C indicates that offal products are among the types of meat that produce lowest exposure to HA.

Item Type: Article
Additional Information: This work was supported by The Ministerio de Ciencia y Tecnología, Spain, Research Project AGL2003-03100
Research Area: Cancer studies
Faculty, School or Research Centre: Faculty of Science (until 2011) > School of Pharmacy and Chemistry
Depositing User: Rosa Busquets
Date Deposited: 08 Jan 2015 11:47
Last Modified: 08 Jan 2015 11:47

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