An analytical method for predicting the geometrical and optical properties of the human lens under accommodation

Sheil, Conor J., Bahrami, Mehdi and Goncharov, Alexander V. (2014) An analytical method for predicting the geometrical and optical properties of the human lens under accommodation. Biomedical Optics Express, 5(5), pp. 1649-1663. ISSN (online) 2156-7085

Full text available as:
[img]
Preview
Text
boe-5-5-1649.pdf - Published Version

Download (1MB) | Preview

Abstract

We present an analytical method to describe the accommodative changes in the human crystalline lens. The method is based on the geometry-invariant lens model, in which the gradient-index (GRIN) iso-indicial contours are coupled to the external shape. This feature ensures that any given number of iso-indicial contours does not change with accommodation, which preserves the optical integrity of the GRIN structure. The coupling also enables us to define the GRIN structure if the radii and asphericities of the external lens surfaces are known. As an example, the accommodative changes in lenticular radii and central thickness were taken from the literature, while the asphericities of the external surfaces were derived analytically by adhering to the basic physical conditions of constant lens volume and its axial position. The resulting changes in lens geometry are consistent with experimental data, and the optical properties are in line with expected values for optical power and spherical aberration. The aim of the paper is to provide an anatomically and optically accurate lens model that is valid for 3 mm pupils and can be used as a new tool for better understanding of accommodation.

Item Type: Article
Additional Information: The authors wish to acknowledge the funding of The Irish Research Council Embark Initiative, application RS/2012/351. This research was also supported by Fight for Sight under grant 1319/1320. This paper was published in Biomedical Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/boe/abstract.cfm?uri=boe-5-5-1649 Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.
Research Area: Biological sciences
Physics
Faculty, School or Research Centre: Faculty of Science, Engineering and Computing (until 2017)
Related URLs:
Depositing User: Mehdi Bahrami
Date Deposited: 03 Jul 2014 08:42
Last Modified: 10 Nov 2014 14:45
DOI: https://doi.org/10.1364/BOE.5.001649
URI: http://eprints.kingston.ac.uk/id/eprint/28297

Actions (Repository Editors)

Item Control Page Item Control Page