Synthesis and biochemical evaluation of a series of methanesulfonate derivatives of 4-hydroxyphenyl ketone as probes of the active site of type 3 OF 17[beta]-hydroxysteroid dehydrogenase family of enzymes

Shah, Kruti, Olusanjo, Moniola S., Cartledge, Tim, Owen, Caroline P. and Ahmed, Sabbir (2009) Synthesis and biochemical evaluation of a series of methanesulfonate derivatives of 4-hydroxyphenyl ketone as probes of the active site of type 3 OF 17[beta]-hydroxysteroid dehydrogenase family of enzymes. Letters in Drug Design and Discovery, 6(7), pp. 518-523. ISSN (print) 1570-1808

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Item Type: Article
Uncontrolled Keywords: 17 beta-hydroxysteroid dehydrogenase, type 3, androgen ablation, enzyme inhibition, methanesulfonate, potential transition-state, approximate representation, inhibitory-activity, drug design, rationalization, 17-beta-hsd3, discovery
Research Area: Chemistry
Pharmacy
Faculty, School or Research Centre: Faculty of Science (until 2011)
Depositing User: Automatic Import Agent
Date Deposited: 08 May 2014 16:18
Last Modified: 08 May 2014 16:18
DOI: https://doi.org/10.2174/157018009789108259
URI: http://eprints.kingston.ac.uk/id/eprint/13829

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