Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation

Hay, Sam, Pudney, Christopher, Hothi, Parvinder, Johannissen, Linus, O., Masgrau, Laura, Pang, Jiayun, Leys, David, Sutcliffe, Michael, J. and Scrutton, Nigel, S. (2008) Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation. Biochemical Society Transactions, 36(1), pp. 16-21. ISSN (print) 0300-5127

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