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Treatment plan comparison in acute and chronic respiratory tract diseases : an observational study of doxophylline vs. theophylline

Mennini, F. S., Sciattella, P., Marcellusi, A., Marcobelli, A., Russo, A. and Caputi, A. P. (2017) Treatment plan comparison in acute and chronic respiratory tract diseases : an observational study of doxophylline vs. theophylline. Expert Review of Pharmacoeconomics & Outcomes Research, 17(5), pp. 503-510. ISSN (print) 1473-7167

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Abstract

BACKGROUND: The main objective of this article is to estimate the global cost related to the use of the two drugs (associated drugs, specialist visits, hospital admissions, plasma drug monitoring). METHODS: The drug prescriptions were extracted from the Information System of the Pharmaceutical Prescriptions of the Marche Region for each ATC code in the years 2008-2012 and the number of patients per year and other outcomes measure were obtained. RESULTS: 13,574 patients were treated with theophylline and 19,426 patients with doxophylline. The number of patients treated was approximately 5,000 per year. Co-prescription with other drugs, use of corticosteroids, mean number of visits and hospital admissions (per 100 patients) were lower for doxophylline vs theophylline (1.55vs5.50, 0.3vs0.7, 2.05vs3.73 and 1.57vs3.3 respectively). The annual mean cost per patient was €187.4 for those treated with doxophylline and €513.5 for theophylline. CONCLUSIONS: In our study, doxophylline resulted to be associated with a reduction of the overall cost.

Item Type: Article
Research Area: Epidemiology and public health
Health services research
Statistics and operational research
Faculty, School or Research Centre: Faculty of Business and Law
Faculty of Business and Law > Kingston Business School (Accounting, Finance and Informatics) (from August 2013)
Related URLs:
Depositing User: Andrea Marcellusi
Date Deposited: 15 Aug 2017 09:02
Last Modified: 28 Sep 2017 14:44
URI: http://eprints.kingston.ac.uk/id/eprint/38771

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