Occurrence of heterocyclic amines in several home-cooked meat dishes of the Spanish diet

Busquets, Rosa, Bordas, Magda, Toribio, Francisca, Puignou, Lluís and Galceran, Maria Teresa (2004) Occurrence of heterocyclic amines in several home-cooked meat dishes of the Spanish diet. Journal of Chromatography B, 802(1), pp. 79-86. ISSN (print) 1570-0232

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Abstract

Heterocyclic amines (HAs) were determined in several of the most frequently eaten meat dishes in Spain such as fried beef hamburger, fried pork loin, fried chicken breast, fried pork sausages, griddled chicken breast, griddled lamb steak and griddled beef steak. All of the products tested were household cooked. The HAs were analysed in the selected meat dishes using an analytical method based on solid-phase extraction followed by liquid chromatography coupled to tandem mass spectrometry. DMIP, MeIQx, 4,8-DiMeIQx, Norharman, Harman, PhIP, Trp-P-1, AαC and MeAαC were the amines most frequently found at concentrations of up to 47 ng g−1 of cooked meat. Glu-P-2, IQ, MeIQ, Glu-P-1, 7,8-DiMeIQx and Trp-P-2 were only found in a few of the meat dishes and their concentrations were lower than 1 ng g−1 of cooked meat. The highest amounts of HAs, especially PhIP and DMIP, were formed in fried chicken breast and the lowest were formed in fried beef hamburger and in fried pork sausages. Daily intake of HAs in Spain was estimated at 606 ng of mutagenic HAs per capita and day, DMIP and PhIP being the main contributors.

Item Type: Article
Additional Information: This work was carried out with financial support from the Commission of the European Community, specific RTD programme “Quality of Life and Management of Living resources”, project CT99-01197 “Heterocyclic Amines in Cooked Foods-Role in Human Health”. Financial support was also provided by the Ministerio de Ciencia y Tecnologı́a, project AGL2000-0948.
Research Area: Agriculture, veterinary and food science
Cancer studies
Chemistry
Faculty, School or Research Centre: Faculty of Science (until 2011) > School of Pharmacy and Chemistry
Depositing User: Rosa Busquets
Date Deposited: 08 Jan 2015 11:44
Last Modified: 08 Jan 2015 11:44
URI: http://eprints.kingston.ac.uk/id/eprint/29341

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