Determination of superoxide dismutase mimetic activity in common culinary herbs

Chohan, Magali, Naughton, Declan P. and Opara, Elizabeth I. (2014) Determination of superoxide dismutase mimetic activity in common culinary herbs. SpringerPlus, 3(578), ISSN (print) 2193-1801

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Abstract

BACKGROUND: Under conditions of oxidative stress, the removal of superoxide, a free radical associated with chronic inflammation, is catalysed by superoxide dismutase (SOD). Thus in addition to acting as an antioxidant, SOD may also be utilized as an anti-inflammatory agent. Some plant derived foods have been shown to have SOD mimetic (SODm) activity however it is not known if this activity is possessed by culinary herbs which have previously been shown to possess both antioxidant and anti-inflammatory properties. The aim of the study was to ascertain if the culinary herbs rosemary, sage and thyme possess SODm activity, and to investigate the influence of cooking and digestion on this activity. Transition metal ion content was also determined to establish if it could likely contribute to any SODm activity detected. FINDINGS: All extracts of uncooked (U), cooked (C) and cooked and digested (C&D) herbs were shown to possess SODm activity, which was significantly correlated with previously determined antioxidant and anti-inflammatory activities of these herbs. SODm activity was significantly increased following (C) and (C&D) for rosemary and sage only. The impact of (C) and (C&D) on the SODm for thyme may have been influenced by its transition metal ion content. CONCLUSIONS: SODm activity may contribute to the herbs' antioxidant and anti-inflammatory activities however the source and significance of this activity need to be established.

Item Type: Article
Additional Information: This work was funded by Kingston University, Biomedical and Pharmaceutical Sciences Research Group.
Uncontrolled Keywords: culinary herbs, speroxide dismutase mimetic activity, antioxidant, anti-inflammatory
Research Area: Allied health professions and studies
Faculty, School or Research Centre: Faculty of Science, Engineering and Computing > School of Life Sciences
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Depositing User: Declan Naughton
Date Deposited: 03 Nov 2014 15:44
Last Modified: 15 Jan 2016 10:32
URI: http://eprints.kingston.ac.uk/id/eprint/29237

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