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Determination of stanozolol and 3[prime]-hydroxystanozolol in rat hair, urine and serum using liquid chromatography tandem mass spectrometry

Deshmukh, Nawed IK, Zachar, Gergely, Petroczi, Andrea, Szekely, Andrea D, Barker, James and Naughton, Declan P (2012) Determination of stanozolol and 3[prime]-hydroxystanozolol in rat hair, urine and serum using liquid chromatography tandem mass spectrometry. Chemistry Central Journal, 6(162), ISSN (online) 1752-153X

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Abstract

The developed methods are sensitive, specific and reproducible for the determination of stanozolol and 3'-hydroxystanozolol in rat hair, urine and serum. These methods can be used for in vivo studies further investigating stanozolol metabolism, but also could be extended for doping testing. Owing to the complementary nature of these tests, with urine and serum giving information on recent drug use and hair providing retrospective information on habitual use, it is suggested that blood or urine tests could accompany hair analysis and thus avoid false doping results.

Item Type: Article
Uncontrolled Keywords: anabolic androgenic steroid, doping, hair analysis, urinalysis, serum analysis, lc-ms/ms
Research Area: Allied health professions and studies
Faculty, School or Research Centre: Faculty of Science, Engineering and Computing > School of Life Sciences
Related URLs:
Depositing User: Declan Naughton
Date Deposited: 02 Jan 2013 15:58
Last Modified: 12 Apr 2013 14:53
URI: http://eprints.kingston.ac.uk/id/eprint/24406

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